LIU, YAJUN
PhD., Professor
Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences
Tel.: +86-532-80662705
Email: liuyj@qibebt.ac.cn
Address: 189 Songling Road, Qingdao, China, 266101
Website: http://mt.qibebt.ac.cn/info/1066/1194.htm
https://orcid.org/0000-0002-0899-5968
Research Interests
1) Lignocellulose bio-depolymerization and bio-degradation mechanism
2) Development of lignocellulose consolidated biosaccharification technology
3) Clostridium-based synthetic biology and development of genetic tools
4) Polyester plastic whole-cell catalyzing degradation
Education and Academic Experience
2001-2005, Ocean University of China, Biology Science, Bachelor
2005-2011, Institute of Microbiology, Chinese Academy of Sciences, Microbiology, Ph.D.
2007-2010, University of Bayreuth, Germany, Microbial Ecology, Ph.D. Joint Education
2011-2014, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Assistant Professor
2014-2020, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Associate Professor
2021-now, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences, Professor
Publications (first author#; corresponding author*)
2020
1. Yan, F, Wei, R*, Cui, Q*, Bornscheuer, UT, Liu, Y-J*. (2020) Thermophilic whole-cell degradation of polyethylene terephthalate using engineered Clostridium thermocellum. Microbial Biotechnology, 10.1111/1751-7915.13580.
2. Liu Y-J*, Li B, Feng Y*, Cui Q*. (2020) Consolidated bio-saccharification: Leading lignocellulose bioconversion into the real world. Biotechnology Advances. 40, 107535.
3. Liu, G.#, Zhao, X.#, Chen, C., Chi, Z., Zhang, Y., Cui, Q., Chi, Z., Liu, Y.-J.* (2020) Robust production of pigment-free pullulan from lignocellulosic hydrolysate by a new fungus co-utilizing glucose and xylose Carbohydrate Polymers. 241, 116400.
4. Yu, G., Liu, S., Feng, X., Zhang, Y., Liu, C., Liu, Y.-J.*, Li, B.*, Cui, Q., Peng, H.*, (2020) Impact of ammonium sulfite-based sequential pretreatment combinations on two distinct saccharification of wheat straw, RSC Advances. 10, 17129-17142.
5. Yao, X., C. Chen, Y. Wang, S. Dong, Y.-J. Liu, Y. Li, Z. Cui, W. Gong, S. Perrett, L. Yao, R. Lamed, E. A. Bayer, Q. Cui and Y. Feng (2020). "Discovery and mechanism of a pH-dependent dual-binding-site switch in the interaction of a pair of protein modules." Science Advances 6(43): eabd7182.
2019
6. Liu, S.#, Liu, Y.-J.#, Feng, Y., Li, B., and Cui, Q.* (2019). Construction of consolidated bio-saccharification biocatalyst and process optimization for highly efficient lignocellulose solubilization. Biotechnology for Biofuels 12, 35.
7. Wei, Z., Chen, C., Liu, Y.J., Dong, S., Li, J., Qi, K., Liu, S., Ding, X., Ortiz De Ora, L., Munoz-Gutierrez, I., Li, Y., Yao, H., Lamed, R., Bayer, E.A., Cui, Q., and Feng, Y.* (2019). Alternative sigmaI/anti-sigmaI factors represent a unique form of bacterial sigma/anti-sigma complex. Nucleic Acids Res 47, 5988-5997.
8. Yao, X., Y. J. Liu, Q. Cui and Y. Feng (2019). "Solution structure of a unicellular microalgae-derived translationally controlled tumor protein revealed both conserved features and structural diversity." Arch Biochem Biophys 665: 23-29.
2018
9. Liu, Y.-J., Qi, K., Zhang, J., Chen, C., Cui, Q.,* and Feng, Y.* (2018). Firmicutes-enriched IS1447 represents a group of IS3-family insertion sequences exhibiting unique + 1 transcriptional slippage. Biotechnology for Biofuels 11, 300.
10. Liu, Y.-J.#, Liu, S.#, Dong, S., Li, R., Feng, Y.*, and Cui, Q.* (2018). Determination of the native features of the exoglucanase Cel48S from Clostridium thermocellum. Biotechnology for Biofuels 11, 6.
11. Li, R., Feng, Y., Liu, S., Qi, K., Cui, Q.*, and Liu, Y.-J.* (2018). Inducing effects of cellulosic hydrolysate components of lignocellulose on cellulosome synthesis in Clostridium thermocellum. Microbial Biotechnology 11, 905-916.
12. Ortiz De Ora, L., Lamed, R., Liu, Y.-J., Xu, J., Cui, Q., Feng, Y., Shoham, Y., Bayer, E.A., and Muñoz-Gutiérrez, I.* (2018). Regulation of biomass degradation by alternative σ factors in cellulolytic clostridia. Scientific Reports 8, 11036.
2017
13. Zhang, J., Liu, S., Li, R., Hong, W., Xiao, Y., Feng, Y., Cui, Q.*, and Liu, Y.-J.* (2017). Efficient whole-cell-catalyzing cellulose saccharification using engineered Clostridium thermocellum. Biotechnol Biofuels 10, 124.
2016
14. Liu, Y.J., Song, X., Li, Y., Xuan, J., Cui, Q., Wang, J., and Feng, Y.* (2016). Low stability of the reduced state of Mycobacterium tuberculosis NrdH redoxin. FEBS Lett 590, 387-395.
15. Cui, G.-Z., Z. Ma, Y.-J. Liu, Y. Feng, Z. Sun, Y. Cheng, X. Song and Q. Cui (2016). "Overexpression of glucose-6-phosphate dehydrogenase enhanced the polyunsaturated fatty acid composition of Aurantiochytrium sp. SD116." Algal Research 19: 138-145.
2015
16. Zhang, J., Liu, Y.-J.*, Cui, G.-Z., and Cui, Q.* (2015). A novel arabinose-inducible genetic operation system developed for Clostridium cellulolyticum. Biotechnol Biofuels 8, 36. (共同通讯)
17. Liu, Y.J., Zhang, J., Cui, G.Z., and Cui, Q. (2015). Current progress of targetron technology: Development, improvement and application in metabolic engineering. Biotechnol J 10, 855-865.
18. Liu, Y.-J. and Q. Cui (2015). Metabolic Engineering of Thermophiles for Biofuel Production. Thermophilic Microorganisms. F.-L. Li. Norfolk, UK, Caister Academic Press.
19. Chen, C., Z. Cui, X. Song, Y. J. Liu, Q. Cui and Y. Feng (2015). "Integration of bacterial expansin-like proteins into cellulosome promotes the cellulose degradation." Appl Microbiol Biotechnol 100(5): 2203–2212.
2014
20. Hong, W., Zhang, J., Feng, Y., Mohr, G., Lambowitz, A.M., Cui, G.-Z., Liu, Y.-J.*, and Cui, Q.* (2014). The contribution of cellulosomal scaffoldins to cellulose hydrolysis by Clostridium thermocellum analyzed by using thermotargetrons. Biotechnol Biofuels 7, 80.
21. Cui, G.Z., Zhang, J., Hong, W., Xu, C., Feng, Y., Cui, Q.*, and Liu, Y.J.* (2014). Improvement of ClosTron for successive gene disruption in Clostridium cellulolyticum using a pyrF-based screening system. Appl Microbiol Biotechnol 98, 313-323.
22. Liu, Y.-J., Cui, G.Z., Hong, W., Zhang, J., Cui, Q.* (2014). Genetic engineering of cellulosome-producing Clostridium strains for cellulosic ethanol production. Chinese Journal of Bioprocess Engineering 12(1): 55-62.
2013
23. Mohr, G., Hong, W., Zhang, J., Cui, G.-Z., Feng, Y., Cui, Q., Liu, Y.-J.*, and Lambowitz, A.M.* (2013). A targetron system for gene targeting in thermophiles and its application in Clostridium thermocellum. PLoS ONE 8, e69032.
24. Liu, Y. J., S. J. Liu, H. L. Drake and M. A. Horn (2013). "Consumers of 4-chloro-2-methylphenoxyacetic acid from agricultural soil and drilosphere harbor cadA, r/sdpA, and tfdA-like gene encoding oxygenases." FEMS Microbiol Ecol 86(1): 114-129.
25. Song, X., Y. Tan, Y.J. Liu, J. Zhang, G. Liu, Y. Feng and Q. Cui (2013). "Different Impacts of Short-Chain Fatty Acids on Saturated and Polyunsaturated Fatty Acid Biosynthesis in Aurantiochytrium sp. SD116." J Agric Food Chem 61(41): 9876-9881.
2012
26. Cui, G.Z., Hong, W., Zhang, J., Li, W.L., Feng, Y., Liu, Y.J.*, and Cui, Q.* (2012). Targeted gene engineering in Clostridium cellulolyticum H10 without methylation. J Microbiol Methods 89, 201-208.
27. Tang, Q.#, Z. Zhao#, Y.J. Liu#, N. Wang, B. Wang, Y. Wang, N. Zhou and S. Liu (2012). "Augmentation of tribenuron methyl removal from polluted soil with Bacillus sp. strain BS2 and indigenous earthworms." J Environ Sci (China) 24(8): 1492-1497.
2011 and earlier
28. Liu, Y. J., A. Zaprasis, S. J. Liu, H. L. Drake and M. A. Horn (2011). "The earthworm Aporrectodea caliginosa stimulates abundance and activity of phenoxyalkanoic acid herbicide degraders." ISME J 5(3): 473-485.
29. Liu, Y. J., S. J. Liu, H. L. Drake and M. A. Horn (2011). "Alphaproteobacteria dominate active 2-methyl-4-chlorophenoxyacetic acid herbicide degraders in agricultural soil and drilosphere." Environ Microbiol 13(4): 991-1009.
30. Zaprasis, A. #, Y. J. Liu#, S. J. Liu, H. L. Drake and M. A. Horn (2010). "Abundance of novel and diverse tfdA-like genes, encoding putative phenoxyalkanoic acid herbicide-degrading dioxygenases, in soil." Appl Environ Microbiol 76(1): 119-128.
31. Li, P. P.#, Y. J. Liu# and S. J. Liu (2009). "Genetic and biochemical identification of the chorismate mutase from Corynebacterium glutamicum." Microbiology 155(Pt 10): 3382-3391.
32. Liu, Y. J.#, P. P. Li#, K. X. Zhao, B. J. Wang, C. Y. Jiang, H. L. Drake and S. J. Liu (2008). "Corynebacterium glutamicum contains 3-deoxy-D-arabino-heptulosonate 7-phosphate synthases that display novel biochemical features." Appl Environ Microbiol 74(17): 5497-5503.
