Song Xiaojin, Ph. D., Professor
Tel.: +86-532-80662705
Email:songxj@qibebt.ac.cn
Address: 189 Songling Road, Qingdao, China, 266101
https://orcid.org/0000-0002-9094-3744
Education and Academic Experience
2023.02 - Present, Professor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences/Shandong Energy Institute
2013.12-2023.02, Associate Professor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences
2010.06-2012.12, Assistant Professor, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences
2008.07-2010.06, Post-doctor in Biology, Ocean University of China
2003.09-2008.07, Doctor of Marine Biology, Ocean University of China 1999.09-2003.07, Bachelor of Life Science, Ocean University of China
Research Interests
Focuses on the regulation of lipid synthesis and the fermentation engineering technology of high-value-added lipid products. Research has been carried out in molecular breeding, fermentation amplification and separation and purification technology of products. Mainly concern on new oleaginous microorganisms containing high-value-added lipid compounds (such as polyunsaturated fatty acids, squalene, terpenes, pigments, etc.).
Main research directions:
1. Regulation of lipid synthesis of microorganisms/microalgae.
2. Fermentation engineering.
Honour
1. Qinghai "Thousand Talents Program" (2021)
2. Qingdao Youth Science and Technology Award (2018)
3. Shandong Provincial Science and Technology Progress Award, second prize (2015)
4. Qingdao Science and Technology Progress Award, third prize (2016)
Publications
1.Wang, Z., Wang, S., Feng, Y., Wan, W., Zhang, H., Bai, X., Cui, Q.*,Song Xiaojin*. 2021. Obtaining high-purity docosahexaenoic acid oil in thraustochytridAurantiochytriumthrough a combined metabolic engineering strategy.J Agric Food Chem, 69(35), 10215-10222.(back cover)
2.Zhang, H., Cui, Q.,Song Xiaojin*. 2021. Research advances on arachidonic acid production by fermentation and genetic modification ofMortierella alpina.World J Microbiol Biotechnol, 37(1), 4.
3. Lu, X., Cui, Y., Chen, Y., Xiao, Y.,Song, Xiaojin, Gao, F., Xiang, Y., Hou, C., Wang, J., Gan, Q., Zheng, X., Lu, Y.*. 2021. Sustainable development of microalgal biotechnology in coastal zone for aquaculture and food.Sci Total Environ, 780, 146369.
4. Wang, S., Lan, C.Z., Wang, Z.J., Wan W.J., Zhang, H.D., Cui, Q.*,Song Xiaojin*, 2020. Optimizing eicosapentaenoic acid production by grafting a heterologous polyketide synthase pathway in the ThraustochytridAurantiochytrium. Journal of Agricultural and Food Chemistry, 68(40), 11253-11260.(back cover)
5. Lan, C., Wang, S., Zhang, H., Wang, Z., Wan, W., Liu, H., Hu, Y., Cui, Q.*,Song Xiaojin*. 2021. Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginousAurantiochytrium.Biotechnol Biofuels, 14(1), 246.
6. Wang, S., Wan, W., Wang, Z., Zhang, H., Liu, H., Arunakumara, K., Cui, Q.,Song Xiaojin*. 2021. A two-stage adaptive laboratory evolution strategy to enhance docosahexaenoic acid synthesis in oleaginous Thraustochytrid.Front Nutr, 8, 795491.
7. Wang, S., Lan, C.Z., Wang, Z.J., Wan W.J., Cui, Q.*,Song Xiaojin*, 2020. PUFA-synthase-specific PPTase enhanced the polyunsaturated fatty acids biosynthesis via the polyketide synthase pathway inAurantiochytrium.Biotechnology for Biofuels,13, 153.
8. Han, X.,Song Xiaojin, Li, F., Lu, Y. 2020. Improving lipid productivity by engineering a control-knob gene in the oleaginous microalgaNannochloropsis oceanica.Metab Eng Commun, 11, e00142.
9. Yang, J.,Song, Xiaojin, Wang, L., Cui, Q.*, 2020. Comprehensive Analysis of Metabolic Alterations inSchizochytriumsp. Strains with Different DHA Content.Journal of Chromatography B, 122193.
10. Cui, G. Z., Wang, Z. J., Hong, W., Liu, Y. J., Chen, Z. H., Cui, Q.*,Song, Xiaojin*, 2019. Enhancing tricarboxylate transportation-related NADPH generation to improve biodiesel production byAurantiochytrium.Algal Research, 40, 101505.
11. Zhang, H., Wang, Z., Feng, Y., Cui, Q.,Song, Xiaojin*, 2019. Phytohormones as stimulators to improve arachidonic acid biosynthesis inMortierella alpina.Enzyme and Microbial Technology, 131, 109381.
12. Wang, Y.,Song, Xiaojin, Feng, Y.; Cui, Q.*, 2019. Changes in peptidomes and Fischer ratios of corn-derived oligopeptides depending on enzyme hydrolysis approaches.Food Chemistry, 297, 124931.
13.Song, Xiaojin, Wang, J., Wang, Y., Feng, Y., Cui, Q., Lu, Y., 2018. Artificial creation ofChlorella pyrenoidosamutants for economic sustainable food production.Bioresource Technology,268, 340-345.
14. Zhang, H., Lu, D., Li, X., Feng, Y., Cui, Q.,Song, Xiaojin*, 2018. Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield inMortierella alpina.BMC Biotechnology, 18, 23.
15.Song, Xiaojin, Ma, Z., Tan, Y., Zhang, H., Cui Q.*, 2017. Wastewater recycling technology for fermentation in polyunsaturated fatty acid production,Bioresource Technology, 235, 79-86.
16. Ma, Z., Tian, M., Tan, Y., Cui, G., Feng, Y., Cui, Q.,Song, Xiaojin*. 2017. Response mechanism of the docosahexaenoic acid producerAurantiochytriumunder cold stress.Algal Research, 25, 191-199.
17. Zhang, H., Feng, Y., Cui, Q.*,Song Xiaojin*2017. Expression ofVitreoscillahemoglobin enhances production of arachidonic acid and lipids inMortierella alpina.BMC Biotechnology, 17(1), 68-77.
