[2012.3.24] Cellulosome assembling modules, cohesin and dockerin, can be divided into three major groups according the sequence homolgy, whereas cohesins and dockerins fromClostridium acetobutylicumare beyond these groups and emanate from a branching point between the type I and type III cohesins/dockerins. To study their structures and interactions, as well as the potential application in artificial cellulosome desgin, we performed the NMR resonance assignments of cohesin and dockerin domains ofC. acetobutylicum. This is the first step to the structural determination of the two domains. Further structurel and interaction studies are in progress.

The first author Zhenling Cui is a Master Degree candidate student. The Metabolomics Group leader Prof. Dr. Qiu Cui and the Assistant Professor Dr. Yifei Li in the group are corresponding authors. This work was supported by One-hundred-Talented-People program (KSCX2-YW-G-066) from Chinese Academy of Sciences and National Basic Research Program of China (973-project, Grant No. 2011CB707404), and the National Natural Science Foundation of China (Grant No. 31100568).

NCBI PubMed

Zhenling Cui, Yifei Li*, Yan Xiao, Yingang Feng, and Qiu Cui* (2013) Resonance assignments of cohesin and dockerin domains fromClostridium acetobutylicumATCC824.Biomol. NMR Assign.7(1), 73-76. [Full text (Publisher website)]

Erratum:Biomol. NMR Assign.7(1), 77.[Full text (Publisher website)]